New rules: Heroin and hydrocodone


Heroin Drug Trafficking Map, DEA

Heroin use is on the increase in the United States. It has been theorized that this is due to more stringent efforts to decrease the availability of oxycodone, resulting in those with a dependence on the drug turning to heroin as a cheap and plentiful replacement. The question is: What has been going on worldwide in the cultivation and distribution of heroin that could make this so?

Availability

As is true for most drugs, availability often influences use. Alcohol is the most obvious example. It is available virtually every day all day in the United States. Only 31 % of people in the United States abstain from drinking and the rate of alcohol use disorders is 7.4%. In contrast in Egypt, a predominantly Muslim country where use of alcohol is not a cultural norm and availability is limited, 95% of people abstain from alcohol and only 0.2% of the population has a current alcohol use disorder.

Where is heroin coming from and how available is it? To get a handle on this we can look at what is exported, from where, and how frequently it is used in the countries it ends up in.

Getting opiates from one place to another is a well-organized and lucrative operation. It is believed that the drug-trafficking of opiates is worth 55-65 billion dollars a year with most of the profit going to the global traffickers who facilitate transport of opiates from the production areas to the end-user.

There are three areas that supply most of the opiates for this large underground economy: Afghanistan, South-East Asia (mostly Myanmar) and Latin America (Mexico and Columbia). Most distinctly, Afghanistan is by far the largest producer, accounting for at least 80-90% of the world illicit opium production over the last few years.

The majority of heroin that enters the United States comes from Mexico and Latin America with a much smaller amount coming from Afghanistan through European and African channels. Recently, there have also been reports of a small proportion of heroin coming from Afghanistan through India to the U.S.

Use

Heroin demand is distributed throughout the world. It has become more available than opium gradually over the last century. Opium use, however, has historically been found to be predominate in Asia and continues to have important markets in Iran, India and Pakistan.

Opioid (opium, morphine, heroin and hydrocodone) use has increased throughout the world with the main increase taking place in the United States. It is estimated that between 28.6 and 38 million people globally have used heroin and prescription pain killers in the last year.

Of all the illicit opioids (opium, morphine and heroin), most people use heroin. Heroin can be smoked, snorted or injected. When injection is used as the primary route of administration it can lead to chronic health issues through exposure to blood-borne diseases such as HIV and Hepatitis C. Heroin is believed to be the most potentially lethal of all illicit drugs due to variations in the purity of the drug and resumption of injection use after a period of abstinence when tolerance to the drug is at a lower threshold.

The Russian Federation and Europe account for one-half of global heroin use. The Russian Federation is estimated to have the highest national consumption. The United Kingdom, Italy, France and Germany have the highest rates of consumption in Europe. The heroin distributed in Europe and the Russian Federation is believed to come almost exclusively from Afghanistan opium.

Comparatively speaking, data suggests that heroin consumption in the United States (20 metric tons) is about a fourth of that which is consumed in Europe. Latin America consumes 5 mt and Canada 1.3 mt of heroin annually.

Back in the USA

Presently, illicit prescription opioids are much more often used than is heroin in the United States. There are concerns that any barriers to the availability of prescription opioids could lead to increases in heroin use. There is already evidence that this has been the case as stricter controls have been implemented.

Most recently, as of October 6, 2014, the FDA has rescheduled all hydrocodone combination products from schedule III to schedule II of the Controlled Substances Act. This allows for much more restrictive prescribing practices which will limit availability of hydrocodone for many people. Given that the Community Epidemiology Work Group (CEWG) operating under the auspices of National Institute on Drug Abuse (NIDA) has reported that heroin continues to be one of the most significant drug abuse concerns across all monitored regions of the United States, the prospect of tightening controls while there is increased heroin availability could be a very lethal combination as those with an opioid dependence turn to a cheaper and less predictable alternative.

REFERENCES
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Community Epidemiology Work Group. January 2014. Epidemiologic trends in drug abuse: Proceedings of the Community Epidemiology Work Group, Highlights and Executive Summary. National Institute of Drug Abuse. Retrieved from http://www.drugabuse.gov/sites/default/files/cewg_jan2014_execsumm.pdf

Federal Register. Vol. 79, No. 163. Friday, August 22, 2014. Rules and Regulations. Drug Enforcement Administration
21 CFR Part 1308 [Docket No. DEA–389]. Retrieved from http://www.gpo.gov/fdsys/pkg/FR-2014-08-22/pdf/2014-19922.pdf

United Nations Office on Drugs and Crime. (2010). World drug report 2010. Retrieved from http://www.unodc.org/unodc/en/data-and-analysis/WDR-2010.html

United Nations Office on Drugs and Crime. (2012). World drug report 2012. Retrieved from http://www.unodc.org/unodc/data-and-analysis/WDR-2012.html

United Nations Office on Drugs and Crime. (2014). World drug report 2014. Retrieved from http://www.unodc.org/wdr2014/en/opiates.html

Caffeine Powder: Emerging Drug Trend?

caffeine powder

 

This is the third in a series of posts about drug trends in the United States and other countries. Previously I looked at drug use in San Francisco and at Burning Man. In this post I will begin to look at emerging drug trends, drugs that are newer on the scene or are making a comeback.

Media Hype

The media do not necessarily report accurately about the harm related to the use of various drugs; drug use tends to be sensationalized. This can lead to people dismissing the negative consequences associated with certain drugs. What is needed is a balanced approach to inform the public of the realistic hazards which may influence a person’s choice to use a drug or not. I will, therefore, look at information from governmental sources such as the National Institute on Drug Abuse (NIDA) as well as press accounts.

Caffeine Powder as Emerging Drug Trend

The most recent emerging drug trend according to the National Institute on Drug Abuse (NIDA) Community Epidemiology Work Group (CEWG) is caffeine powder. Some highlights from the latest report about caffeine powder include:

        • Ohio high school senior died due to overdose of powdered caffeine
        • Bags of bulk caffeine powder offered online and bought for weight loss and athletic performance
        • One teaspoon of caffeine is equal to 25 cups of coffee which is a lethal amount
        • Overdose can cause erratic and fast heartbeat, seizures, vomiting, diarrhea and disorientation
        • Very easy to overdose because it is difficult to measure correct dosage with ordinary kitchen implements
        • Recommended that caffeine powder be avoided altogether
        • Parents should be aware of this form of caffeine and be alert to the hazard

A Sign of Things to Come? Perhaps…

This CEWG warning about caffeine powder is dated July 2014 and appears to be most immediately in response to the death of an Ohio teenager in May 2014. I looked at the the CEWG regional reports that were presented in June 2014, after this incident. None of the reporting areas in the United States list caffeine powder as a drug trend.

While not occurring in the United States, another recent death took place in Britain when a 23 year-old man took two teaspoons of caffeine powder and washed it down with an energy drink in 2010.

Dr. Henry Spiller, who directs the poison control center at Nationwide Children’s Hospital in Columbus, Ohio, said that in the last year there have been 30 caffeine powder overdoses reported to poison control centers nationally. He also reported that his poison control center had three reports of people hospitalized due to misuse of caffeine powder.

FDA Concerns

Caffeine has been on the Food and Drug Administration (FDA) and American Poison Control’s radar for several years now. In 2010 the FDA warned manufacturers to take beverages containing alcohol and caffeine off the market. Wrigley’s Gum also took their caffeinated gum off the market in 2013 after the FDA expressed concerns.

In Conclusion

Powdered caffeine is marketed online and in stores and can be far more potentially lethal than either energy drinks or caffeine tablets since measuring the amount is difficult and the lethality of the dose is indeterminate. It therefore comes as no surprise that the FDA is presently considering regulatory action.

There is more information about the facts and fiction of caffeine in its various forms here.